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Rhodium-Catalyzed Rapid Synthesis of Substituted Phenols from Cyclobutenones and Alkynes or Alkenes via C—C Bond Cleavage.

✍ Scribed by Teruyuki Kondo; Masatsugu Niimi; Masato Nomura; Kenji Wada; Take-aki Mitsudo


Publisher
John Wiley and Sons
Year
2007
Weight
22 KB
Volume
38
Category
Article
ISSN
0931-7597

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Reaction of 2-Hydroxybenzaldehydes with Alkynes, Alkenes, or Allenes via Cleavage of the Aldehyde C-H Bond Using a Rhodium Catalyst System. -Aldehyde (I) smoothly reacts with internal and terminal alkynes to give alkenoylphenols in good to excellent yields. The substituents of acetylene influence th