✦ LIBER ✦

A new phenanthroindolizidine alkaloid fromTylophora indica

✍ Scribed by Dhiman, Mini; Khanna, Amit; Manju, Sreedharannair L.

Book ID: 119932384
Publisher: Versita
Year: 2013
Tongue: English
Weight: 194 KB
Volume: 67
Category: Article
ISSN: 0366-6352
DOI: 10.2478/s11696-012-0265-9

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

A new phenanthroindolizidine alkaloid, 3-O-demethyl tylophorinidine (VI), was isolated from the aerial (leaves and stem) parts of Tylophora indica and characterized using different spectral techniques. Gel chromatography and reverse phase preparative HPLC were used for sample purification. The new alkaloid, VI, was screened for anticancer activity against a panel of different cancer cell lines and it showed significant anticancer activity with IC50 value in the range of 0.89–1.40 μM.

📜 SIMILAR VOLUMES

Rare Phenanthroindolizidine Alkaloids an

Rare Phenanthroindolizidine Alkaloids and a Substituted Phenanthrene, Tyloindane, from Tylophora indica

✍ Ali, M.; Ansari, S. H.; Qadry, J. S. 📂 Article 📅 1991 🏛 American Chemical Society 🌐 English ⚖ 513 KB

Fuyuziphine, a new alkaloid from Fumaria

Fuyuziphine, a new alkaloid from Fumaria indica

✍ Pandey, M. B.; Singh, A. K.; Singh, J. P.; Singh, V. P.; Pandey, V. B. 📂 Article 📅 2008 🏛 Taylor and Francis Group 🌐 English ⚖ 110 KB

Isolation of phenanthroindolizidine alka

Isolation of phenanthroindolizidine alkaloids and a novel biphenylhexahydroindolizine alkaloid fromFicus hispida

✍ S. R. Venkatachalam; N. B. Mulchandani 📂 Article 📅 1982 🏛 Springer 🌐 English ⚖ 342 KB

Design, synthesis, antiviral activity, a

Design, synthesis, antiviral activity, and SARs of 13a-substituted phenanthroindolizidine alkaloid derivatives

✍ Su, Bo; Cai, Chunlong; Deng, Meng; Liang, Demin; Wang, Lizhong; Wang, Qingmin 📂 Article 📅 2014 🏛 Elsevier Science 🌐 English ⚖ 412 KB

A seco-phthalideisoquinoline alkaloid fr

A seco-phthalideisoquinoline alkaloid from Fumaria indica seeds

✍ Y.C. Tripathi; V.B. Pandey; N.K.R. Pathak; M. Biswas 📂 Article 📅 1988 🏛 Elsevier Science 🌐 English ⚖ 178 KB

Alkaloids of tylophora III: New alkaloid

Alkaloids of tylophora III: New alkaloids of Tylophora indica (burm) merrill and tylophora dalzellii hook. f

✍ Koppaka V. Rao; Richard A. Wilson; Bernice Cummings 📂 Article 📅 1971 🏛 John Wiley and Sons 🌐 English ⚖ 235 KB

jection of the phlogistic agent. This was done to offset any possible error caused by the difference in the size of the animals used. The standard error of the mean (SEM) was calculated according to the formula given by Burn et al. (10): where s j = SEM, = mean value, y = any single value, N = tota