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A new perspective on the antiatherosclerotic activity of Ca2+-channel blockers

✍ Scribed by L. H. BLOCK; L. R. EMMONS

Book ID
114726869
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
269 KB
Volume
20
Category
Article
ISSN
0014-2972

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Structure-activity relationship of Ca2+channel blockers: A study using conformational analysis and chemometric methods
✍ L. Belvisi; S. Brossa; A. Salimbeni; C. Scolastico; R. Todeschini πŸ“‚ Article πŸ“… 1991 πŸ› Springer Netherlands 🌐 English βš– 753 KB

A structure-activity relationship study has been done on 8 compounds with the activity known as 'Ca2+ channel blockers'. Conformational analysis was carried out using a molecular mechanics method. The 3D-QSAR approach was used and the most polar functional groups present in all the molecules were co