𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A New Peroxy-multiflorane Triterpene Ester from the Processed Seeds of Trichosanthes kirilowii

✍ Scribed by Yue-Ping Ma; Ning Li; Jian Gao; Ke-Ling Fu; Ying Qin; Guo-Yu Li; Jin-Hui Wang

Publisher
John Wiley and Sons
Year
2011
Tongue
German
Weight
259 KB
Volume
94
Category
Article
ISSN
0018-019X

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

A new peroxy‐multiflorane triterpene ester, (3__α__,5__α__,8__α__,20__α__)‐5,8‐epidioxymultiflora‐6,9(11)‐diene‐3,29‐diol 3,29‐dibenzoate (1), was isolated from the processed seeds of Trichosanthes kirilowii, together with the two known related derivatives 2 and 3, and the two known steroids 4 and 5. Compounds 2, 4, and 5 were isolated from the genus Trichosanthes for the first time. The structure of compound 1 was established by NMR, HR‐MS, and CD analyses. Compounds 1–3 were tested for their in vitro cytotoxicity against human‐tumor cell lines (Hela, HL‐60, and MCF‐7) and anti‐inflammatory activity (LPS‐induced B lymphocyte cells) with the MTT method.

📜 SIMILAR VOLUMES

Multiflorane Triterpene Esters from the
Multiflorane Triterpene Esters from the Seeds of Trichosanthes kirilowii
✍ Tao Wu; Xue-Mei Cheng; S. W. Annie Bligh; Gui-Xin Chou; Zheng-Tao Wang; Alan Bas 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 German ⚖ 107 KB

## Abstract Two new multiflorane triterpene esters, (3__α__,7__β__)‐3,7,29‐trihydroxymultiflor‐8‐ene‐3,29‐diyl dibenzoate (**2**) and (3__α__)‐3,29‐dihydroxy‐7‐oxomultiflor‐8‐ene‐3,29‐diyl dibenzoate (**3**) have been isolated from the CHCl~3~ extract of the seeds of __Trichosanthes kirilowii__, to