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A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate

✍ Scribed by Rameh, Lucia E.; Tolias, Kimberley F.; Duckworth, Brian C.; Cantley, Lewis C.

Book ID
109786863
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
348 KB
Volume
390
Category
Article
ISSN
0028-0836

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## Abstract The type I phosphatidylinositol 4‐phosphate 5‐kinases (PI4P5K) phosphorylate phosphatidylinositol 4‐phosphate [PI(4)P] to produce phosphatidylinositol 4,5‐bisphosphate [PI(4,5)P~2~]. PI(4,5)P~2~ has been implicated in signal transduction, receptor mediated endocytosis, vesicle trafficki