A new nortriterpenoid ketol from two adiantum species

✍ Scribed by A. Zaman; A. Prakash; G. Berti; F. Bottari; B. Macchia; A. Marsili; I. Morelli

• Publisher: Elsevier Science
• Year: 1966
• Tongue: French
• Weight: 185 KB
• Volume: 7
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)70007-4

✦ Synopsis

During a study of constituents of the fern Adiantum venustum Don conducted at Aligarh it was found that the plant contains a new triterpenoid compound. The same compound had been obtained in Pisa from Adiantum capillus-Veneris L., but had not been investigated because of the very small amount that was available. On isolation of somewhat larger amounts in Aligarh a joint study lea to the identification of the compound as 21-hydroxy-30-norhopan-22-one (21-hydroxyadiantone, The compound was isolated from the petroleum ether extract of Adiantum venustum, which also contains a large excess od adiantone (1) and traces of 3-filicene (2,3). It crystallizes out from the extract, on concentration and cooling, along with adiantone, and is freed from the latter by taking advantage of its sparing solubility in benzene. It pras further purified by repeated crystallization from benzene-chloroform and finally recrystallized from pyridine-dioxane. It has m.p. 281-284O (sec.) and gives a positive Cotton effect curve,