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Adenanthusone, a New Ursane Type Nortriterpenoid from Isodon adenanthus

✍ Scribed by Wei Xiang; Qi-Shi Song; Hong-Jie Zhang; Rong-Tao Li; Zhi Na; Han-Dong Sun


Publisher
John Wiley and Sons
Year
2004
Tongue
German
Weight
186 KB
Volume
87
Category
Article
ISSN
0018-019X

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✦ Synopsis


Abstract

A new ursane‐type nortriterpenoid, adenanthusone (=(11__α__,12__α__)‐4‐demethyl‐11,12‐epoxy‐3,13‐dihydroxy‐2‐oxoursa‐3,20(30)‐diene‐28‐oic acid γ‐lactone; 1) was isolated from Isodon adenanthus. Its structure was determined by NMR spectra and X‐ray crystallographic diffraction analysis. The biogenetic implication of the nortriterpene is discussed.


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## Abstract The new ursane‐type triterpenoid glycoside, asiaticoside G (I), is isolated along with five known triterpenoids and four flavonoids from the leaves of Centella asiatica. Their chemical structures are elucidated and bioactivities are evaluated.