𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A new mutation in the coding region of the bovine leptin gene associated with feed intake

✍ Scribed by R. Lagonigro; P. Wiener; F. Pilla; J. A. Woolliams; J. L. Williams

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
85 KB
Volume
34
Category
Article
ISSN
0268-9146

No coin nor oath required. For personal study only.

✦ Synopsis

Summary

An experimental cattle population was screened for polymorphisms in the leptin gene and five SNPs were found in the regions containing the coding sequences. The association of these polymorphisms with feed intake and fat‐related traits was evaluated. The results suggest an association between a polymorphism in exon 2, described here for the first time, and feed intake. Individuals with genotype A/T at this position had 19% greater mean feed intake than individuals with genotype A/A. There was also evidence for a link between leptin haplotypes and some fat‐related traits.

📜 SIMILAR VOLUMES

A novel mutation in the β-protein coding
A novel mutation in the β-protein coding region of the amyloid β-protein precursor (APP) gene
✍ Milagros Balbín; Magnus Abrahamson; Lars Gustafson; Karin Nilsson; Arne Brun; An 📂 Article 📅 1992 🏛 Springer 🌐 English ⚖ 329 KB

A novel mutation, a C to T transition at base pair 2124 in exon 17 of the amyloid beta-protein precursor (APP) gene, has been identified by direct sequencing of amplified DNA from two Alzheimer's disease (AD) patients. A simple oligonucleotide-hybridization procedure was developed to allow populatio

Two new mutations in the HIF2A gene asso
Two new mutations in the HIF2A gene associated with erythrocytosis
✍ Melanie J. Percy; Yu Jin Chung; Claire Harrison; Jane Mercieca; A. Victor Hoffbr 📂 Article 📅 2012 🏛 John Wiley and Sons 🌐 English ⚖ 928 KB

## Abstract Congenital or familial erythrocytosis/polycythemia can have many causes, and an emerging cause is genetic disruption of the oxygen‐sensing pathway that regulates the __Erythropoietin__ (__EPO__) gene. More specifically, recent studies have identified erythrocytosis‐associated mutations