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A new allelic variant in the bovine prion protein gene (PRNP) coding region

✍ Scribed by J Schläpfer; N Saitbekova; C Gaillard; G Dolf


Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
402 KB
Volume
30
Category
Article
ISSN
0268-9146

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Mutation of the human prion protein gene (PRNP) open reading frame (ORF) accounts for almost all reported familial concurrence of prion disease. The more common mutations globally: octapeptide repeat insertions, P102L, D178N, E200K, and V210I have occurred in large multigenerational pedigrees and di