A new method to study regeneration in vitro of the adult frog sciatic sensory axons

Effects of protein kinase inhibitors on

Effects of protein kinase inhibitors on regeneration in vitro of adult frog sciatic sensory axons

✍ P. A. R. Ekström; H. Bergstrand; A. Edström 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 844 KB

The effects of protein kinase inhibitors on regeneration in vitro of adult frog sciatic sensory axons were tested. Regeneration of crush-injured nerves for 8 days in serum-free medium was inhibited by staurosporine (100 nM) and H-7 (100 pM), which are both known to inhibit protein kinase C. With the