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A New Method for the Synthesis of Symmetrical Disubstituted Pyrazines

✍ Scribed by Rojas, Nora; Grillasca, Yvonne; Acosta, Alejandrina; Audelo, Irene; de la Mora, Gustavo García

Book ID
120614639
Publisher
Journal of Heterocyclic Chemistry
Year
2013
Tongue
English
Weight
165 KB
Volume
50
Category
Article
ISSN
0022-152X

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✍ Fouad Bentiss; Michel Lagrenée 📂 Article 📅 1999 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 182 KB 👁 1 views

## Abstract Several new 2,5‐disubstituted 1,3,4‐oxadiazoles have been synthesized in good yields by reaction of aromatic acids with hydrazine dihydrochloride in a mixture of orthophosphoric acid, phosphorus pentoxide and, in general, with addition of phosphorus oxychloride to the reaction mixture.