A new method for the synthesis of ketones: The palladium-catalyzed cross-coupling of acid chlorides with arylboronic acids

✍ Scribed by Mustapha Haddach; James R. McCarthy

• Book ID: 104261261
• Publisher: Elsevier Science
• Year: 1999
• Tongue: French
• Weight: 171 KB
• Volume: 40
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(99)00476-1

✦ Synopsis

The cross-coupling reaction of acid chlorides with arylboronic acids, using catalytic amounts of Pd(PPh3)4 and five equivalents Cs2CO3, under anhydrous conditions provides a new method for the synthesis of ketones in good to moderate yields.