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A new method for the synthesis of branched oligoribonucleotides using a fully protected branched triribonucleoside diphosphate unit

✍ Scribed by Mitsuo Sekine; Jarmo Heikkila; Tsujiaki Hata

Book ID: 104228109
Publisher: Elsevier Science
Year: 1987
Tongue: French
Weight: 266 KB
Volume: 28
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)96815-1

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✦ Synopsis

A fully protected key intermediate (2 for the synthesis of branched oliqoribonucleotides was prepared by a four-step reaction from N6-benzoyladenosine 3' -phosphorodianilidate (3. To demonstrate the utility of this synthetic unit, G a branched ribonucleotide of CUGAC was synthesized.

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