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A New Method for the Stereoselective Synthesis of α-Substituted Serine Amino Acid Analogues

✍ Scribed by Lane, Jonathan W.; Halcomb, Randall L.


Book ID
118746614
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
86 KB
Volume
5
Category
Article
ISSN
1523-7060

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Facile stereoselective synthesis of γ-su
✍ Martin Smrcina; Pavel Majer; Eva Majerová; Tatiana A. Guerassina; Michael A. Eis 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 459 KB

A lacile slereoselcctive melhod Ior the synthesis of y-substituted, y-mnino acids from of amino acids was developed. The key step of the procedurc is complete reduction of Ihe keto functionality of ot-~unino acyl Meldruln's acid by sodium acetoxyborohydride. The resulting amino alkyl Meldrum's acid