It was recently found in our laboratory that peptides with high optical purities are synthesized in excellent yields by oxidation-reduction condensation
A new method for the reduction of esters
โ Scribed by H. J. Prins
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 139 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0165-0513
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๐ SIMILAR VOLUMES
## Abstract For Abstract see ChemInform Abstract in Full Text.
Reduction of nitronyl nitroxides using hexamethylenetetramine is a very convenient method for preparing the corresponding imino nitroxides and 2-imidazoline N-oxides.
The reduction of alkylphenylmalonates and dialkylmalonates with LiAI(O-t-Bu)3H proceeds with selective reduction of one of the ester functionalities to provide the hydroxy-ester derivatives in good yields.
A simple andjexible algorithm is presented tojnd stable reduced models, provided the original system has a set of dominant poles. The proposed technique applies to the multivariable case as well and provides a parameter to control the approximationfor small and large t.