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A new method for the construction of the pyrrole ring by the carbonylcobalt-catalyzed reaction of trimethylsilyl cyanide with acetylenes. Its scope and limitations

โœ Scribed by Chatani, Naoto; Hanafusa, Terukiyo


Book ID
127274788
Publisher
American Chemical Society
Year
1991
Tongue
English
Weight
724 KB
Volume
56
Category
Article
ISSN
0022-3263

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โœ Yoko Nambu; Takeshi Endo ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 238 KB

By use of cesium fluoride as a catalyst, aryl or alkyl glycidyl ethers were ring-opened by aryl trimethylsilyl ether to produce O-protected aryloxyhydrins with a quantitative regioselectivity for the first time. Alkyl silyl ether was ineffective for this ring-opening. Hy the regioselective ring-ope