✦ LIBER ✦
A novel reaction for the functionalization of epoxy resins: New regio- and chemoselective ring-opening of epoxides with aryl silyl ether catalyzed by cesium fluoride
✍ Scribed by Yoko Nambu; Takeshi Endo
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- French
- Weight
- 238 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
By use of cesium fluoride as a catalyst, aryl or alkyl glycidyl ethers were ring-opened by aryl trimethylsilyl ether to produce O-protected aryloxyhydrins with a quantitative regioselectivity for the first time. Alkyl silyl ether was ineffective for this ring-opening.
Hy the regioselective ring-opening of epoxides with trimethylsilyl aside', silyl halides2, silyl amides3, and silylated arylseleno14, various O-protected functionalized hydrins prospective as synthetic intermediates were obtained.