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A New Method for the Catalytic Aldol Reaction to Ketones.

✍ Scribed by Kounosuke Oisaki; Yutaka Suto; Motomu Kanai; Masakatsu Shibasaki


Publisher
John Wiley and Sons
Year
2003
Weight
218 KB
Volume
34
Category
Article
ISSN
0931-7597

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Nucleophilic Addition of Nitrones to Ket
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A new organic reaction has been discovered in which nitrones react with carbonyl compounds in an aldoltype reaction to give functionalized beta-hydroxynitrones. The alpha-carbon atom of the nitrone undergoes a nucleophilic addition reaction to electron-deficient ketones, such as alpha-ketoesters, al