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A new method for labelling of monoclonal antibodies and their fragments with technetium-99m

✍ Scribed by Joiris, Etienne; Bastin, Benoit; Thornback, John R


Book ID
122378549
Publisher
Elsevier Science
Year
1991
Weight
333 KB
Volume
18
Category
Article
ISSN
0883-2897

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## Abstract The present study refers to the preparation of a 99m‐Technetium labelled murine monoclonal antibody for clinical application. The monoclonal antibody was incubated with a 20fold molar excess of 2‐iminothiolane. The free thiol groups created, were capable of binding reduced technetium. L