bonds have been carried out in different solvents to investigate the formation and stabilization of @-turn structures and to determine the stereochemistry of the disulfide linkage. Both peptides have three-dimensional structures with a type I1 P-turn, as derived from quantitative nuclear Overhauser
A new method for disulfide analysis of peptides
β Scribed by W.L. Anderson; D.B. Wetlaufer
- Book ID
- 107711690
- Publisher
- Elsevier Science
- Year
- 1975
- Tongue
- English
- Weight
- 561 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0003-2697
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π SIMILAR VOLUMES
A selective and efficient method for disulfide bond formation in pepti\_' \_de~\_ \_ u "tdizin8 cartxm ~de in dichlommethane in the presence of tetrabutylammonium fluoride (TBAF) is described. The reactloa gt, ceeded rapidly and no side reaction was observed with nuclcophific amino acids such as Met
A new procedure is described for identification of disulfide bonds in peptides by fast atom bombardment mass spectrometry (FABMS). Prolonged bombardment of a disulfide-containing peptide in solution by a high-energy xenon beam results in gradual reduction of the disulfide bond. The reduction is the