✦ LIBER ✦

A new metabolite of propachlor isolated from germfree rat excreta

✍ Scribed by V. J. Feil; J. E. Bakke; G. L. Larsen; B. E. Gustafsson

Publisher: John Wiley and Sons
Year: 1981
Tongue: English
Weight: 310 KB
Volume: 8
Category: Article
ISSN: 1076-5174
DOI: 10.1002/bms.1200080102

No coin nor oath required. For personal study only.

✦ Synopsis

2-[S-(N-Acetyl

)cysteine]-isopropylacetanilide sulfoxide was isolated from the excreta of germfree rats given oral doses of 2-chloro-N-isopropylacetanilide. The metabolite was characterized by mass and nuclear magnetic resonance spectrometry on samples isolated from rats dosed with [l-"C]and [2-'3C]-2-chloro-N-isopropylacetanilide. Artifact formation upon reaction of the sulfoxide with alcoholic HC1 is discussed.

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