A new level of 18F
β Scribed by R.M. Freeman; P.A. De Young; L.J. Satkowiak; M.A. Xapsos; J.J. Kolata
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 493 KB
- Volume
- 385
- Category
- Article
- ISSN
- 0375-9474
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SUI(IvLRY ## Ritanserin has been labelled with 18F to visualize the serotoninergic receptors by Positron Emission Tomography (PET). The synthesis was carried out by a nucleophilic substitution of a nitro substituent of a ni trophenylketone by 18F-and then addition of a Grignard reagent to the ket
A new route to aryl [18F]fluorides without electron withdrawing ring substituents has been developed. [18F]Fluorobenzaldehydes, prepared from no-carrier-added (NCA) [18F]fluoride using nucleophilic aromatic substitution of fluoro or nitro groups, were decarbonylated using palladium on charcoal (Pd-C