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A new LAGE-1 peptide recognized by cytolytic T lymphocytes on HLA-A68 tumors

✍ Scribed by Zhaojun Sun; Bernard Lethé; Yi Zhang; Vincenzo Russo; Didier Colau; Vincent Stroobant; Thierry Boon; Pierre van der Bruggen


Publisher
Springer-Verlag
Year
2005
Tongue
English
Weight
356 KB
Volume
55
Category
Article
ISSN
0340-7004

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The MAGE-encoded antigens that are recognized by cytolytic T lymphocytes (CTL) are shared by many tumors and are strictly tumor specific. Clinical trials involving therapeutic vaccination of cancer patients with MAGE antigenic peptides or proteins are in progress. To increase the range of patients e