A MAGE-1 antigenic peptide recognized by human cytolytic T lymphocytes on HLA-A2 tumor cells
β Scribed by Sabrina Ottaviani; Yi Zhang; Thierry Boon; Pierre der Bruggen
- Publisher
- Springer-Verlag
- Year
- 2005
- Tongue
- English
- Weight
- 292 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0340-7004
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The MAGE-encoded antigens that are recognized by cytolytic T lymphocytes (CTL) are shared by many tumors and are strictly tumor specific. Clinical trials involving therapeutic vaccination of cancer patients with MAGE antigenic peptides or proteins are in progress. To increase the range of patients e
## Abstract Treatment of chondrosarcomas is limited to resection because these tumors are unresponsive to standard adjuvant treatments, such as chemotherapy and radiation. We have previously shown that highβgrade chondrosarcomas express unspecified members of the Melanoma Antigen (MAGE) gene family