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A New Isoquinoline Alkaloid from the Marine Sponge Haliclona Species

โœ Scribed by Rashid, Mohammad A.; Gustafson, Kirk R.; Boyd, Michael R.

Book ID
120599759
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
29 KB
Volume
64
Category
Article
ISSN
0163-3864

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Halitulin, a new cytotoxic alkaloid from
Halitulin, a new cytotoxic alkaloid from the marine sponge Haliclona tulearensis
โœ Yoel Kashman; Ganit Koren-Goldshlager; M.D.Garcia Gravalos; Michael Schleyer ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 257 KB

Halitulin (2), a novel bisquinolinylpyrrole has been isolated from the sponge Haliclona tulearensis. Its structure was elucidated mainly on the basis of spectroscopic data as well as chemical modifications. Halitulin was found to be cytotoxic against several tumor cells: P-388, A-549, HT-29 and MEL-