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A new heritable fragile site on human chromosome 3

✍ Scribed by A. MARKKANEN; S. KNUUTILA; A. DE LA CHAPELLE

Book ID
114808981
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
70 KB
Volume
99
Category
Article
ISSN
0018-0661

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Heritable fragile sites on human chromos
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The fragile site at Xq27 which is associated with X-linked retardation with macroorchidism has been studied in 21 retarded males. These males were from 12 families, and studies of nine of the familes were possible. Detection of carrier females is difficult, especially with increasing age. The fragil

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✍ G. R. Sutherland; P. Leonard πŸ“‚ Article πŸ“… 1979 πŸ› Springer 🌐 English βš– 305 KB

The chromosomal gaps associated with fragile sites at 2q11, 10q23, 11q13, 16q22, 20p11 and Xq27 do not stain with silver nitrate as do NOR regions of the acrocentric chromosomes.