A new haplotype of PDCD1 is associated with rheumatoid arthritis in Hong Kong Chinese
✍ Scribed by Eric Kai-Pang Kong; Ludmila Prokunina-Olsson; Wilfred Hing-Sang Wong; Chak-Sing Lau; Tak-Mao Chan; Marta Alarcón-Riquelme; Yu-Lung Lau
- Book ID
- 101648203
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 61 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0004-3591
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## Abstract ## Objective To study the frequency of allele A of polymorphism PD‐1.3 of the __PDCD1__ gene in patients with rheumatoid arthritis (RA) and its subsets, based on the presence of rheumatoid factor (RF) and the shared epitope (SE) alleles. ## Methods A total of 1,175 patients with RA a
## Objective: In the era of postgenomic research, linkage- and association-based strategies are beginning to reveal novel complex disease genes. using such an approach, a functional haplotype of the peptidylarginine deiminase 4 gene (padi4) has recently been identified as a gene conferring suscepti