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A New Family of β-Hairpin Mimetics Based on a Trypsin Inhibitor from Sunflower Seeds

✍ Scribed by Anne Descours; Kerstin Moehle; Annabelle Renard; John A. Robinson


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
200 KB
Volume
3
Category
Article
ISSN
1439-4227

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Combinatorial diversity in hypervariable b-hairpin loops is exploited by the immune system to select binding sites on antibodies for a wide variety of different protein antigens. In a first step towards mimicking this strategy in vitro, for the selection of novel protein ligands, an approach is desc