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A new facile synthesis of 5-aryl-4-trifluoroacetyl-6-trifluoromethyl-3,4-dihydro-2H-1,3,4-oxadiazines from arylaldehydes

✍ Scribed by Yasuhiro Kamitori; Masaru Hojo; Ryōichi Masuda; Yoshihiko Kawamura; Kazuyoshi Kawasaki; Junya Ida

Publisher
Elsevier Science
Year
1990
Tongue
French
Weight
125 KB
Volume
31
Category
Article
ISSN
0040-4039

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✦ Synopsis

By reaction with an excess of trifluoroacetic anhydride, title compounds 4 were synthesized from C-trifluoroacetylated hydrazones 1 which are readily obtainable by trifluoroacetylation of arylaldehyde dimethylhydrazones. Oxadiazine derivatives have attracted much attention of organic chemists from interests in their biological activities. 1,283 Recently we reported synthesis of 5-aryl-

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