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A new facile synthesis of 2-aminothiazole-5-carboxylates

โœ Scribed by Rulin Zhao; Stacey Gove; Joseph E Sundeen; Bang-Chi Chen

Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
47 KB
Volume
42
Category
Article
ISSN
0040-4039

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A new facile method for the synthesis of
A new facile method for the synthesis of 1-arylimidazole-5-carboxylates
โœ Bang-Chi Chen; Mark S Bednarz; Rulin Zhao; Joseph E Sundeen; Ping Chen; Zhongqi ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 139 KB

A new facile method for the preparation of 1-arylimidazole-5-carboxylates was developed. The new method involved reaction of anilines and ethyl glyoxylate in methanol to give a-anilino-a-methoxyacetates followed by cyclization with TosMIC, aording 1-arylimidazole-5-carboxylates in two steps in 40ยฑ94