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A New Enantioselective Synthesis of Milnacipran and an Analogue by Catalytic Asymmetric Cyclopropanation

✍ Scribed by Michael P. Doyle; Wenhao Hu


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
94 KB
Volume
343
Category
Article
ISSN
1615-4150

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Asymmetric Synthesis of 5-(1-Hydroxyalkyl)tetrazoles by Catalytic Enantioselective Passerini-Type Reactions\*\* Scheme 1. Catalytic enantioselective synthesis of 5-(1-hydroxyalkyl)tetrazole 1 by three-component Passerini reaction (P-3CR). Figure 1. Catalysts screened for enantioselective synthesis