Thermal reactions of 3-phenyl-5-arylamino-1,2,4-oxadiazoles I and II were investigated. Neat heating at ca. 250ΠC for 6 hours afforded H 2 O, benzonitrile, arylcyanamides, arylamines, azobenzene, benzimidazole derivatives, and 3,3Π-diphenyl-5,5Π-bis[1,2,4-oxadiazolyl]. Analogous results were obtaine
β¦ LIBER β¦
A new convenient synthesis of 5-aryl-2-(arylamino)-1,3,4-oxadiazole derivatives
β Scribed by Sanjeev Kumar
- Book ID
- 111491554
- Publisher
- Versita
- Year
- 2012
- Tongue
- English
- Weight
- 140 KB
- Volume
- 66
- Category
- Article
- ISSN
- 0366-6352
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β¦ Synopsis
Abstract
Electrical energy offers numerous benefits for conducting a synthesis, including increased reaction rates, yield enhancements and cleaner chemistries. 5-Aryl-2-(arylamino)-1,3,4-oxadiazoles were synthesised directly from acylthiosemicarbazide on the platinum electrode under controlled potential electrolysis in an undivided cell assembly in acetonitrile.
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