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A New Class of Potent Anti-inflammatory Agents; Synthesis of 9α,11β-Dihalocorticosteroids

✍ Scribed by Robinson, C. H.; Finckenor, L.; Oliveto, Eugene P.; Gould, David


Book ID
126324078
Publisher
American Chemical Society
Year
1959
Tongue
English
Weight
684 KB
Volume
81
Category
Article
ISSN
0002-7863

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9-pyridylidenefluorenes, a new class of
✍ N. P. Buu-Hoï; F. Delbarre; P. Jacquignon; H. Brouilhet; A. Rose; J. F. Sabathie 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 163 KB

## Abstract The condensation of fluorene with the three formylpyridines and 2‐formyl‐6‐methylpyridine has been investigated, and the 9‐pyridylidenefluorenes obtained have been tested in rats for anti‐inflammatory activity. 9‐(3‐Pyridylidene)fluorene proved the most potent compound, with an activity