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A new chromosome anomaly in acute lymphoblastic leukemia (ALL)

✍ Scribed by H. Berghe; G. David; A. Broeckaert-Van Orshoven; A. Louwagie; R. Verwilghen; M. Casteels-Van Daele; E. Eggermont; R. Eeckels

Book ID
104707726
Publisher
Springer
Year
1979
Tongue
English
Weight
421 KB
Volume
46
Category
Article
ISSN
0340-6717

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✦ Synopsis

A new chromosome anomaly in acute lymphoblastic leukemia (ALL) is reported. Three, possibly four, patients showed an identical karyotype anomaly, characterized by a (4;11)(q13;q22) reciprocal translocation. This anomaly has not so far been found in lymphoproliferative disorders other than ALL. Two of the patients had congenital leukemia, but the anomaly described appears to be more characteristic of ALL than of congenital leukemia, and may help the clinician in establishing the diagnosis of ALL.

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