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A new chromosomal breakpoint in Ph positive, bcr negative chronic myelogenous leukemia: Report of a case

✍ Scribed by Massimo Negrini; Antonella Tallarico; Isabella Pazzi; Antonella Castagnoli; Antonio Cuneo; Gian Luigi Castoldi


Book ID
119105566
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
382 KB
Volume
61
Category
Article
ISSN
0165-4608

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Translocation of BCR to chromosome 9: A
✍ Dr. Anne Hagemeijer; Arjan Buijs; Elizabeth Smit; Bart Janssen; Geert-Jan Creeme πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 781 KB

## Abstract Leukemic cells from two patients with Philadelphia‐negative chronic myeloid leukemia (CML) were investigated: I) Cytogenetics showed a normal 46.XY karyotype in both cases, 2) molecular studies revealed rearrangement of the M‐BCR region and formation of __BCR‐ABL__ fusion mRNA with b2a2