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A new chemoenzymatic approach to the synthesis of penems

โœ Scribed by Altamura, Maria; Cesti, Pietro; Francalanci, Franco; Marchi, Marcello; Cambiaghi, Stefano

Book ID
124150101
Publisher
Royal Society of Chemistry
Year
1989
Weight
660 KB
Volume
7
Category
Article
ISSN
1472-7781

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A practical chemoenzymatic approach to t
A practical chemoenzymatic approach to the synthesis of 3-hydroxy metabolites of tibolone
โœ Patrizia Ferraboschi; Diego Colombo; Shahrzad Reza-Elahi ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 107 KB

Stereoselective preparation of the 3-hydroxy metabolites of tibolone is easily accomplished by diastereoselective Candida antarctica lipase B-catalyzed transformations of 3a-and 3b-alcohols or acetates mixtures in organic solvents, in suitable amounts for biological studies.