Reduction of 3t3-benzoyloxy-14a,15c~-epoxy-5c~-cholest-7-ene with either lithium triethylborohydride or lithium aluminum hydride (4 molar excess) gave 5c~-cholest-8( 14)-en-3~,15a-diol in high yield. Reduction of the epoxy ester with lithium triethylborodeuteride or lithium aluminum deuteride (4 mol
✦ LIBER ✦
A new chemical synthesis of 5α-cholest-8(14)-en-3β,5α-diol
✍ Scribed by Edward J Parish; Chi Luo; Terrence L Boos
- Book ID
- 108313213
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 57 KB
- Volume
- 109
- Category
- Article
- ISSN
- 0009-3084
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The X-ray crystal structure of 3~-benzoyloxy-6a-chloro-5a-cholest-7-ene (IV) was determined by the heavy atom method and ref'med to R ---0.063 (space group P2s, a --11.364, b = 11.089, c --12.232,/~ = 99.43 °, Z ---2). IV was previously shown to be an important intermediate in the acid-catalyzed iso
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