A new asymmetric grignard cross-coupling reaction via an alkyl group isomerization catalyzed by chiral phosphine-nickel complexes

High stereoselectivity in asymmetric Gri

High stereoselectivity in asymmetric Grignard cross-coupling catalyzed by nickel complexes of chiral (aminoalkylferrocenyl)phosphines

✍ Hayashi, Tamio; Tajika, Masatoyo; Tamao, Kohei; Kumada, Makoto 📂 Article 📅 1976 🏛 American Chemical Society 🌐 English ⚖ 297 KB

Chiral β-dimethylaminoalkylphosphines. H

Chiral β-dimethylaminoalkylphosphines. Highly efficient ligands for a nickel complex catalyzed asymmetric grignard cross-coupling reaction

✍ Tamio Hayashi; Motoo Fukushima; Mitsuo Konishi; Makoto Kumada 📂 Article 📅 1980 🏛 Elsevier Science 🌐 French ⚖ 276 KB

Chiral B-dimethylaminoalkylphosphines were prepared starting with amino acids, (S)alanine, (S)-phenylalanine, (R)-phenylglycine, (S)-valine, and (R)-tert-leucine. The chiral phosphines were found to be highly efficient ligands for a nickel catalyzed asymmetric Grignard cross-coupling reaction (38Q4%

Alkyl group isomerization in the cross-c

Alkyl group isomerization in the cross-coupling reaction of secondary alkyl Grignard reagents with organic halides in the presence of nickel-phosphine complexes as catalysts

✍ Tamao, Kohei; Kiso, Yoshihisa; Sumitani, Koji; Kumada, Makoto 📂 Article 📅 1972 🏛 American Chemical Society 🌐 English ⚖ 284 KB

Asymmetric cross-coupling reaction of se

Asymmetric cross-coupling reaction of sec-alkyl grignard reagents with organic halides in the presence of a chiral phosphine-nickel complex as a catalyst

✍ Yoshihisa Kiso; Kohei Tamao; Norio Miyake; Keiji Yamamoto; Makoto Kumada 📂 Article 📅 1974 🏛 Elsevier Science 🌐 French ⚖ 233 KB

Asymmetric synthesis catalyzed by chiral

Asymmetric synthesis catalyzed by chiral ferrocenylphosphine-transition-metal complexes. 6. Practical asymmetric synthesis of 1,1'-binaphthyls via asymmetric cross-coupling with a chiral [(alkoxyalkyl)ferrocenyl]monophosphine/nickel catalyst

✍ Hayashi, Tamio.; Hayashizaki, Keiichi.; Kiyoi, Takao.; Ito, Yoshihiko. 📂 Article 📅 1988 🏛 American Chemical Society 🌐 English ⚖ 606 KB

Asymmetric synthesis catalyzed by chiral

Asymmetric synthesis catalyzed by chiral ferrocenylphosphine-transition-metal complexes. 6. Practical asymmetric synthesis of 1,1'-binaphthyls via asymmetric cross-coupling with a chiral [(alkoxyalkyl)ferrocenyl]monophosphine/nickel catalyst

✍ Hayashi, Tamio.; Hayashizaki, Keiichi.; Kiyoi, Takao.; Ito, Yoshihiko. 📂 Article 📅 1988 🏛 American Chemical Society 🌐 English ⚖ 606 KB

averaged. The concentration of the free amide remaining after complexation could then be calculated from the extinction coefficient and used to determine the apparent equilibrium constant. The equilibrium between free amide and the sec-butyllithium-amide complex was established within less than ca.