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A new assay for collagenolytic activity

โœ Scribed by Chia-Ling Hu; George Crombie; Carl Franzblau


Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
349 KB
Volume
88
Category
Article
ISSN
0003-2697

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โœฆ Synopsis


A new assay procedure for the determination of collagenolytic activity is presented. The substrate can be prepared by simple reduction of the purified acidsoluble rat tail tendon collagen with NaB3H4. Collagenase activity is determined by measurement of soluble tritiated collagen peptides released. It has proven to be a method with a high degree of sensitivity and reproducibility.


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