A new approach to the synthesis of substituted 2(1H)-quinolinones
✍ Scribed by George Theodoridis; Patricia Malamas
- Book ID
- 112130017
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1991
- Tongue
- English
- Weight
- 253 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0022-152X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Addition of Crignard or organolithium reagents to R-(a-haloacyl)-g-alkylsubstituted anthranilonitriles (e.g. B-(2-bromopropionyl)-N-methyl-2-cyanoaniline) induced anion formation followed by cyclization to I-amino-2quinolinones (e.g. I-amino-1,3-dimethyl-2-quinolinone (1Q)). Substrates lacking a-hyd
## Abstract magnified image The reactivity of 3‐[(dimethylamino)prop‐2‐enoyl]‐4‐hydroxyl‐1‐methylquinolin‐2(1__H__)‐one (**2**) towards different nucleophilic and electrophilic reagents was investigated. The convenient synthesis of several 3‐heterocyclyl‐quinolinones such as 3‐pyridazinyl‐ **10, 1