A New Approach to Highly Substituted Cyclopentanoids from a Concise Formal Synthesis of (+)-Roseophilin
β Scribed by Kerr, Daniel J.; Flynn, Bernard L.
- Book ID
- 120245238
- Publisher
- American Chemical Society
- Year
- 2012
- Tongue
- English
- Weight
- 390 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1523-7060
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A direct stereocontrolled route for the construction of highly substituted cyclopentanones 10a-d has been developed starting from aeyclic ketones 5a,b. The key step involves copper(I)-eatalysed stezeoselective photocycloaddition of the dienes 6a-d followed by stereospecific rearrangement of the cycl