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A New and Practical Synthesis of Octafluoro[2.2]paracyclophane

โœ Scribed by Dolbier,, William R.; Rong, Xiao X.; Xu, Yuelian; Beach, William F.


Book ID
126961771
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
181 KB
Volume
62
Category
Article
ISSN
0022-3263

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A new and convenient synthesis of octafluoro[2,2]paracyclophane and dodeca-fluoro[2,2]paracyclophane is reported. It is accomplished by treatment of 1,4-bis(halodifluoromethyl)benzene with PbBr 2 /Al in DMF at room temperature via the cyclocoupling of the reactive intermediate a,a,a%a%-tetrafluoro-p