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A New and High-Yielding Synthesis of Unstable Pyrroles via a Modified Clauson—Kaas Reaction.

✍ Scribed by Brendon S. Gourlay; Peter P. Molesworth; John H. Ryan; Jason A. Smith


Publisher
John Wiley and Sons
Year
2006
Weight
21 KB
Volume
37
Category
Article
ISSN
0931-7597

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## Abstract We synthesized 2'‐deoxy‐2'‐[^18^F]fluorouridine (**7**) as a radiotracer for positron emission tomography from a new nosylate precursor (**6**). This new precursor was synthesized from uridine in four steps. The overall synthetic yield was 9.4% and we have high stability of >98% purity