A new and convenient synthesis of N-substituted perhydroazepines from adipaldehyde and primary amines with tetracarbonylhydridoferrate, HFe(CO), as a selective reducing agent

Selective synthesis of N-(cyclohexymethy

Selective synthesis of N-(cyclohexymethyl)-N-alkylamines from primary amines and pimelaldehyde using tetracarbonylhydridoferrate, HFe(CO)4−, as a reducing reagent

✍ Chul Shim Sang; Gil Kwon Young; Hoon Doh Chil; Seok Kim Hong; Jeong Kim Tae 📂 Article 📅 1990 🏛 Elsevier Science 🌐 French ⚖ 142 KB

Sunmary: Treatment of primary amines with pimelaldehyde in the presence of tetracarbonylhydridoferrate, HFe(CO)q at roan temperature under atmospheric pressure of CO for 24 hours gave selectively corresponding N-(cyclohexylmethyl)~N-alkylamines in moderate yields. Recently, we have reported that a