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A neuronal function of the tumor suppressor protein merlin

โœ Scribed by Alexander Schulz,Ansgar Zoch,Helen Morrison

Book ID
126393548
Publisher
Springer (Biomed Central Ltd.)
Year
2014
Tongue
English
Weight
664 KB
Volume
2
Category
Article
ISSN
2051-5960

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The neurofibromatosis 2 (NF2) tumor suppressor gene product, merlin (schwannomin) forms an intramolecular association that is required for negative growth regulation in vitro and in vivo. In an effort to develop a molecular model for merlin relevant to its tumor suppressor function, we further chara