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A mutation that increases the activity of nonsense suppressors in Escherichia coli

✍ Scribed by Davidoff-Abelson, Rosa ;Mindich, Leonard

Book ID
118287385
Publisher
Springer
Year
1978
Tongue
English
Weight
853 KB
Volume
159
Category
Article
ISSN
0026-8925

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A temperature-sensitive mutant of Escher
A temperature-sensitive mutant of Escherichia coli that shows enhanced misreading of UAG/A and increased efficiency for tRNA nonsense suppressors
✍ RydΓ©n, S. M. ;Isaksson, L. A. πŸ“‚ Article πŸ“… 1984 πŸ› Springer 🌐 English βš– 940 KB

A spontaneous mutant was isolated that harbors a weak suppressing activity towards a UAG mutation, together with an inability to grow at 43 degrees C in rich medium. The mutation is shown to be associated with an increased misreading of UAG at certain codon contexts and UAA. UGA, missense or framesh