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A mutation in the gene for the β′ subunit of Escherichia coli RNA polymerase which specifically affects transcription of the rpoBC operon

✍ Scribed by Joel B. Kirschbaum


Book ID
118918016
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
741 KB
Volume
119
Category
Article
ISSN
0022-2836

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Evidence for Co-transcription of the RNA
✍ Newman, Andrew J. ;Linn, Thomas G. ;Hayward, Richard S. 📂 Article 📅 1979 🏛 Springer 🌐 English ⚖ 941 KB

The adjacent genes rpoB and rpoC code for the beta and beta' subunits of RNA polymerase in Escherichia coli, and are cotranscribed in the order given. The nearest known genes to rpoB are rplL and rplA,J,K, which code for ribosomal proteins, and which are transcribed in the same direction as the poly

Mutation to rifampicin resistance at the
✍ Lisitsyn, N. A. ;Sverdlov, E. D. ;Moiseyeva, E. P. ;Danilevskaya, O. N. ;Nikifor 📂 Article 📅 1984 🏛 Springer 🌐 English ⚖ 208 KB

The unusual recombinant plasmid pRC19 carrying the N-terminal fragment of the Escherichia coli RNA polymerase rpoB gene was found to specify high level rifampicin resistance of E. coli cells. Sequence analysis of this plasmid revealed one substitution only: transversion G----T, leading to amino acid

The effect of rifampicin upon the transc
✍ Bass, I. A. ;Danilevskaya, O. N. ;Mekhedov, S. L. ;Fedoseeva, V. B. ;Gorlenko, Z 📂 Article 📅 1979 🏛 Springer 🌐 English ⚖ 728 KB

We studied the rate of synthesis of beta-and beta'-subunits of DNA-dependent RNA polymerase and the rate of beta-polypeptide mRNA synthesis in rifampicin-treated bacteria. The chosen antibiotic doses did not significantly inhibit the total RNA and protein synthesis in rifampicin-sensitive bacteria.