A monoclonal antibody recognizing a polymorphic determinant on HLA-DR antigens except DR 7 and DRw9
β Scribed by K. Ogasawara; M. Kasahara; T. Nakayama; N. Ishikawa; H. Kunikane; S. Hawkin; H. Kojima; H. Ikeda; A. Wakisaka; Y. Kikuchi; M. Aizawa
- Book ID
- 115093748
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 226 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0001-2815
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We describe here two monoclonal antibodies with HLA-DR7 serologic specificity. The antibodies, S FR 16-DR7M, a cytotoxic rat IgM antibody of high affinity, and SFR16-DR7G, a noncytotoxic antibody of the rat IgG 2a class, react with only DR7-positive cells in radioimmunoassay. The cytotoxic activity