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A monoclonal antibody detecting a possible public specificity of the HLA-C locus

โœ Scribed by Corazon L. Dejelo; William E. Braun; Andrea A. Zachary; Alan Smerglia; Linda Clark

Book ID
115093759
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
297 KB
Volume
28
Category
Article
ISSN
0001-2815

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Detection of a novel HLA-DQ specificity:
Detection of a novel HLA-DQ specificity: serological and immunochemical analyses by a monoclonal antibody
โœ Naoshi Ishikawa; Hiroshi Kojima; Tsuguyo Nakayama; Hiroshi Kunikane; Shuichi Haw ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 725 KB

A monoclonal antibody (mAb) with a novel human B-cell allospecificity was produced by immunizing a C3H/He mouse with the human B lymphoblastoid cell line EBV-Wa (HLA-DR4/Dw15/DQblank homozygous). The mAb, termed HU-46, reacted with B cells from not only DR4/Dwl5-positive individuals but also certain