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A molecular programme for the specification of germ cell fate in mice

โœ Scribed by Saitou, Mitinori; Barton, Sheila C.; Surani, M. Azim

Book ID
109890418
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
825 KB
Volume
418
Category
Article
ISSN
0028-0836

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Background: In mice, germ cells are specified through signalling between layers of cells comprising the primitive embryo. The function of Dppa3 (also known as Pgc7 or stella), a gene expressed in primordial germ cells at the time of their emergence in gastrulating embryos, is unknown, but a recent s